# 22 LR Full Size Handguns - Guns For Sale

Shop .22 LR full size handguns built for rimfire range work, target practice, and accurate plinking. This catalog tag includes precision semi-auto pistols such as the Browning Buck Mark Lite, Beretta 87 Target, and Beretta U22 Neos models with 4.5 inch and 6.0 inch configurations.

Explore full size .22 LR pistols with features like Inox, matte gray, and matte blue finishes, plus target-oriented profiles designed for steady handling and consistent sight alignment. These handguns are well suited for shooters comparing full size rimfire pistols for practice, training, and recreational accuracy.

## Featured Firearms (254 total)

| Product | Caliber | Price |
|---------|---------|-------|
| [Glock G44 .22 LR Pistol - FDE, Lightweight & Accurate, 10rd](https://gunsnation.com/p/glock-g44-22-lr-pistol-fde-lightweight-accurate-10rd/UCC75exrv) | .22 LR | - |
| [Taurus TX22 OD Green .22LR Pistol - 16-Round Striker-Fired](https://gunsnation.com/p/taurus-tx22-od-green-22lr-pistol-16-round-striker-fired/UCClj85Ka) | .22 LR | - |
| [Taurus TX22 Cyan - .22 LR Striker, 16 Rds, Lightweight Precision](https://gunsnation.com/p/taurus-tx22-cyan-22-lr-striker-16-rds-lightweight-precision/UCClj86T0) | .22 LR | - |
| [Taurus TX22 FDE .22LR Pistol - Lightweight, Accurate, 10+1 Capacity](https://gunsnation.com/p/taurus-tx22-fde-22lr-pistol-lightweight-accurate-10-1-capacity/UCClj85Nm) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite Blue .22 LR Pistol - Precision & Versatility](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-blue-22-lr-pistol-precision-versatility/UCCy79GOP) | .22 LR | - |
| [Ruger Mark IV Target Precision .22 LR Pistol](https://gunsnation.com/p/ruger-mark-iv-target-precision-22-lr-pistol/UCCy796eD) | .22 LR | - |
| [Taurus TX22 .22LR Full-Size Pistol - Ergonomic, Lightweight, Accurate](https://gunsnation.com/p/taurus-tx22-22lr-full-size-pistol-ergonomic-lightweight-accurate/UCClj85SE) | .22 LR | - |
| [Taurus TX22 Full-Size .22LR Pistol, Matte Black, 16+1 Capacity](https://gunsnation.com/p/taurus-tx22-full-size-22lr-pistol-matte-black-16-1-capacity/UCClj85hb) | .22 LR | - |
| [Ruger 22 Charger Takedown - 15-Rd .22 LR Compact Semi-Auto Pistol](https://gunsnation.com/p/ruger-22-charger-takedown-15-rd-22-lr-compact-semi-auto-pistol/UCCy77cxo) | .22 LR | - |
| [Beretta M9-22 Black .22 LR Pistol - Precision & Versatility](https://gunsnation.com/p/beretta-m9-22-black-22-lr-pistol-precision-versatility/UC1RzNJqf) | .22 LR | - |
| [Taurus TX22 .22 LR SAO Pistol - Ergonomic & Lightweight Shooter](https://gunsnation.com/p/taurus-tx22-22-lr-sao-pistol-ergonomic-lightweight-shooter/UCClj85HV) | .22 LR | - |
| [Phoenix Arms HP22A Versatile .22LR Dual Barrel Range Kit](https://gunsnation.com/p/phoenix-arms-hp22a-versatile-22lr-dual-barrel-range-kit/UCDGjTIOL) | .22 LR | - |
| [Kel-Tec CP33 .22lr High-Capacity Performance Pistol - Midnight Bronze](https://gunsnation.com/p/kel-tec-cp33-22lr-high-capacity-performance-pistol-midnight-bronze/UCBHUnnVV) | .22 LR | - |
| [Taurus TX22: Lightweight .22 LR Pistol with Precision Trigger & Grip](https://gunsnation.com/p/taurus-tx22-lightweight-22-lr-pistol-with-precision-trigger-grip/UCClj85Zq) | .22 LR | - |
| [Beretta U22 Neos Inox: Precision .22 LR Semi-Auto Pistol](https://gunsnation.com/p/beretta-u22-neos-inox-precision-22-lr-semi-auto-pistol/UC1RzNcNL) | .22 LR | - |
| [Browning Buck Mark Lite URX - .22 LR Aluminum Pistol, Ergonomic & Light](https://gunsnation.com/p/browning-buck-mark-lite-urx-22-lr-aluminum-pistol-ergonomic-light/UCPm7mds) | .22 LR | - |
| [Browning Buck Mark Contour URX .22 LR Precision Pistol](https://gunsnation.com/p/browning-buck-mark-contour-urx-22-lr-precision-pistol/UCPm67QE) | .22 LR | - |
| [Browning Buck Mark Contour URX .22 LR Semi-Auto Pistol](https://gunsnation.com/p/browning-buck-mark-contour-urx-22-lr-semi-auto-pistol/UCPm67Q0) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR Pistol - Lightweight Precision](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-pistol-lightweight-precision/UCCy79GLw) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR Pistol - Lightweight Precision](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-pistol-lightweight-precision/UCCy79GNQ) | .22 LR | - |

*Showing 20 of 254 products*

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*Data from [GunsNation](https://gunsnation.com)*