# Most Powerful Handguns - Guns For Sale

The most powerful production handguns are chambered in rounds like .500 S&W Magnum, .460 S&W Magnum, .454 Casull, and .44 Magnum, and are primarily used for big game hunting and protection against large predators. The Smith & Wesson 500 in .500 S&W Magnum is widely cited as the most powerful production revolver. The Smith & Wesson 460XVR in .460 S&W Magnum is also compatible with .454 Casull and .45 Colt. The Ruger Super Redhawk is available in .454 Casull and .44 Magnum. The Desert Eagle in .50 Action Express is a semi-automatic option. All are high-recoil firearms suited to experienced shooters.

## Featured Firearms (25 total)

| Product | Caliber | Price |
|---------|---------|-------|
| [Magnum Research BFR .500 JRH Revolver - 5.5" Bisley Stainless](https://gunsnation.com/p/magnum-research-bfr-500-jrh-revolver-5-5-bisley-stainless/UCDOuZ5Zt) | .500 JRH | - |
| [Desert Eagle .50 AE Distressed White Semi-Auto Pistol](https://gunsnation.com/p/desert-eagle-50-ae-distressed-white-semi-auto-pistol/UCDOuZ5VD) | .50 AE | - |
| [Magnum Research BFR .500 Linebaugh Revolver - 7.5" Barrel, 5-Rds](https://gunsnation.com/p/magnum-research-bfr-500-linebaugh-revolver-7-5-barrel-5-rds/UCDOuZ5rj) | .500 Linebaugh | - |
| [BFR Thunder .45-70 GOVT Stainless Revolver - Power & Precision](https://gunsnation.com/p/bfr-thunder-45-70-govt-stainless-revolver-power-precision/UCDOuZ69B) | .45-70 Government | - |
| [Desert Eagle .50 AE Trump Edition - Stainless Power Pistol](https://gunsnation.com/p/desert-eagle-50-ae-trump-edition-stainless-power-pistol/UCDOuZ5zV) | .50 AE | - |
| [Magnum Research Desert Eagle MK XIX .50 AE 6" Black Semi-Auto Pistol](https://gunsnation.com/p/magnum-research-desert-eagle-mk-xix-50-ae-6-black-semi-auto-pistol/UCDOuZ68g) | .50 AE | - |
| [Magnum Research BFR .454 Casull 6.5" Stainless Revolver](https://gunsnation.com/p/magnum-research-bfr-454-casull-6-5-stainless-revolver/UCDOuZ65i) | .454 Casull | - |
| [Desert Eagle .50 AE Mark XIX Burnt Bronze Power Pistol](https://gunsnation.com/p/desert-eagle-50-ae-mark-xix-burnt-bronze-power-pistol/UCDOuZ5Eo) | .50 AE | - |
| [Ruger Super Redhawk .454 Casull - 5" Satin Stainless Powerhouse](https://gunsnation.com/p/ruger-super-redhawk-454-casull-5-satin-stainless-powerhouse/UCCy77eTd) | .454 Casull | - |
| [Magnum Research BFR .500 S&W Revolver - 10" Stainless Powerhouse](https://gunsnation.com/p/magnum-research-bfr-500-s-w-revolver-10-stainless-powerhouse/UCDOuYrEb) | .500 S&W Magnum | - |
| [Taurus Raging Bull .454 Casull Revolver - Power & Precision Mastery](https://gunsnation.com/p/taurus-raging-bull-454-casull-revolver-power-precision-mastery/UCClj5Ydu) | .454 Casull | - |
| [Magnum BFR .460 S&W Magnum Revolver, 10" Barrel Powerhouse](https://gunsnation.com/p/magnum-bfr-460-s-w-magnum-revolver-10-barrel-powerhouse/UCDOuYsTW) | .460 S&W Magnum | - |
| [Magnum Research BFR .45-70 GOVT Revolver - 7.5" Stainless Steel](https://gunsnation.com/p/magnum-research-bfr-45-70-govt-revolver-7-5-stainless-steel/UCDOuZ5Yn) | .45-70 Government | - |
| [Magnum Research Desert Eagle L6 Mark XIX .50 AE - Black Oxide Powerhouse](https://gunsnation.com/p/magnum-research-desert-eagle-l6-mark-xix-50-ae-black-oxide-powerhouse/UCDOuZ6AH) | .50 AE | - |
| [Magnum Research BFR .45-70 Govt Revolver - 7.5" Stainless Powerhouse](https://gunsnation.com/p/magnum-research-bfr-45-70-govt-revolver-7-5-stainless-powerhouse/UCDOuYq3X) | .45-70 Government | - |
| [Magnum Research BFR .500 S&W Magnum 7.5" SS Power Revolver](https://gunsnation.com/p/magnum-research-bfr-500-s-w-magnum-7-5-ss-power-revolver/UCDOuYrEU) | .500 S&W Magnum | - |
| [Magnum BFR .500 S&W - 10" Stainless Power Revolver](https://gunsnation.com/p/magnum-bfr-500-s-w-10-stainless-power-revolver/UCDOuZ5aH) | .500 S&W Magnum | - |
| [S&W 460XVR Magnum Revolver - Precision Powerhouse](https://gunsnation.com/p/s-w-460xvr-magnum-revolver-precision-powerhouse/UCODeElY) | .460 S&W Magnum | - |
| [Magnum Research BFR .45-70: Stainless Hunter's Powerhouse Revolver](https://gunsnation.com/p/magnum-research-bfr-45-70-stainless-hunter-s-powerhouse-revolver/UCDOuZ5Yu) | .45-70 Government | - |
| [Smith & Wesson 460XVR Magnum Hunter, 14" Precision Barrel Revolver](https://gunsnation.com/p/smith-wesson-460xvr-magnum-hunter-14-precision-barrel-revolver/UCODdXMt) | .460 S&W Magnum | - |

*Showing 20 of 25 products*

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*Data from [GunsNation](https://gunsnation.com)*