# Ruger Full Size Handguns - Guns For Sale

Ruger Full Size Handguns brings together range-focused centerfire and rimfire pistols, including SR1911 models in 9mm, .45 ACP, and 10mm, along with Ruger-57, Mark IV, MKIII Hunter, and 22/45 Lite variants. This selection covers stainless 1911 profiles, target pistols, lightweight .22 LR semi-autos, and 5.7x28mm options with modern capacity.

Browse Ruger full-size pistols built for precision shooting, classic single-action handling, and steady full-frame control. Product options include G10 grips, satin and stainless finishes, threaded or lightweight-style rimfire designs, 4.25 inch and 6 inch barrel formats, and configurations suited for target work, training, and collection-focused buyers.

## Featured Firearms (98 total)

| Product | Caliber | Price |
|---------|---------|-------|
| [Ruger Mark IV 22/45 Lite Blue .22 LR Pistol - Precision & Versatility](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-blue-22-lr-pistol-precision-versatility/UCCy79GOP) | .22 LR | - |
| [Ruger SR1911 Competition - .45 ACP Precision Match Pistol](https://gunsnation.com/p/ruger-sr1911-competition-45-acp-precision-match-pistol/UCCy77hkh) | .45 ACP | - |
| [Ruger American 9mm Duty: Compact Self-Defense Semi-Auto Pistol](https://gunsnation.com/p/ruger-american-9mm-duty-compact-self-defense-semi-auto-pistol/UCCy77meg) | 9mm | - |
| [Ruger Mark IV 22/45 Lite .22 LR Pistol - Lightweight Precision](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-pistol-lightweight-precision/UCCy79GLw) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR Pistol - Lightweight Precision](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-pistol-lightweight-precision/UCCy79GNQ) | .22 LR | - |
| [Ruger Mark IV 22/45 Tactical .22 LR Pistol - 10-Round Mag](https://gunsnation.com/p/ruger-mark-iv-22-45-tactical-22-lr-pistol-10-round-mag/UCCy79GLR) | .22 LR | - |
| [Ruger Duty .45 ACP Semi-Auto Pistol - Precision & Reliability](https://gunsnation.com/p/ruger-duty-45-acp-semi-auto-pistol-precision-reliability/UCCy77mhl) | .45 ACP | - |
| [Ruger Mark IV 22/45 Lite OR .22 LR Pistol - Optics & Suppressor Ready](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-or-22-lr-pistol-optics-suppressor-ready/UCCy79GSK) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR - Precision Target Pistol Gen 4](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-precision-target-pistol-gen-4/UCCy79GNu) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR Pistol - Lightweight Precision](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-pistol-lightweight-precision/UCCy79GQ0) | .22 LR | - |
| [Ruger American Pro 9mm - Competition Elite Pistol](https://gunsnation.com/p/ruger-american-pro-9mm-competition-elite-pistol/UCCy77mgY) | 9mm | - |
| [Ruger Mark IV 75th Edition .22 LR Precision Semi-Auto Pistol](https://gunsnation.com/p/ruger-mark-iv-75th-edition-22-lr-precision-semi-auto-pistol/UCCy796di) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR Semi-Auto Pistol, 10rd, 4.4" Barrel](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-semi-auto-pistol-10rd-4-4-barrel/UCCy79GRi) | .22 LR | - |
| [Ruger Mark IV Target .22LR Pistol - Precision 5.5" Bull Barrel, 10+1rd](https://gunsnation.com/p/ruger-mark-iv-target-22lr-pistol-precision-5-5-bull-barrel-10-1rd/UCCy796dp) | .22 LR | - |
| [Ruger Mark IV 70th Anniversary .22 LR Semi-Auto Pistol - Precision Classic](https://gunsnation.com/p/ruger-mark-iv-70th-anniversary-22-lr-semi-auto-pistol-precision-classic/UCCy796cS) | .22 LR | - |
| [Ruger Mark IV 22/45 Lite .22 LR SAO Pistol - Precision & Lightweight](https://gunsnation.com/p/ruger-mark-iv-22-45-lite-22-lr-sao-pistol-precision-lightweight/UCCy79GOk) | .22 LR | - |
| [Ruger 22 Charger Go Wild Camo - .22 LR Semi-Auto Precision Pistol](https://gunsnation.com/p/ruger-22-charger-go-wild-camo-22-lr-semi-auto-precision-pistol/UCCy77cxh) | .22 LR | - |
| [Ruger Mark IV Target Elite .22 LR - Precision Bull Barrel Pistol](https://gunsnation.com/p/ruger-mark-iv-target-elite-22-lr-precision-bull-barrel-pistol/UCCy796dK) | .22 LR | - |
| [Ruger Security-9 Compact: Versatile 9mm Semi-Auto Pistol](https://gunsnation.com/p/ruger-security-9-compact-versatile-9mm-semi-auto-pistol/UCCy77a4C) | 9mm | - |
| [Ruger Mark IV CAHSS .22 LR Semi-Auto Pistol - Blue Finish, 10-Rounds](https://gunsnation.com/p/ruger-mark-iv-cahss-22-lr-semi-auto-pistol-blue-finish-10-rounds/UCCy796fo) | .22 LR | - |

*Showing 20 of 98 products*

## Related Tags

- [Concealed Carry](https://gunsnation.com/t/concealed-carry)
- [Home Defense](https://gunsnation.com/t/home-defense)
- [Tactical](https://gunsnation.com/t/tactical)
- [Hunting](https://gunsnation.com/t/hunting)
- [Optic-Ready](https://gunsnation.com/t/optic-ready)
- [Best 9mm Handguns](https://gunsnation.com/t/best-9mm-handguns)
- [Military Classic](https://gunsnation.com/t/military-classic)
- [Match Pistols](https://gunsnation.com/t/match-pistols)

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*Data from [GunsNation](https://gunsnation.com)*