.22 LR Semi-Automatic Handguns - Guns For Sale
Explore .22 LR semi-automatic handguns built for rimfire range time, target practice, plinking, and low-recoil training. This selection includes compact pistols like the Armalite ISSC M22 and Beretta 21A Bobcat, plus full-size target and 1911-style options such as the Ruger 22/45, Ruger Mark III, Mauser 1911, and Chiappa 1911-22.
Browse models with practical barrel lengths, familiar controls, black, stainless, OD green, and FDE finishes, and range-ready configurations like the FN 502 Tactical and Standard Manufacturing Jackhammer. These .22 LR semi-auto pistols fit shoppers looking for a lighter-shooting handgun for practice sessions, skill building, or classic rimfire fun.
GunsNation lists 108 .22 LR Semi-Automatic Handguns listings from multiple verified dealers. Compare them side by side to find the best price.
Frequently asked questions
- How many .22 LR Semi-Automatic Handguns listings are on GunsNation?
- GunsNation currently aggregates 108 .22 LR Semi-Automatic Handguns listings from verified dealers, so you can compare prices in one place.
.22 LRRuger Mark III .22 LR 5.5in Stainless
.22 LRTaurus TX-22 .22 LR 4.1in Cyan
.22 LRKel-Tec P17 .22 LR 3.8in Green/Black
.22 LRKel-Tec P17 .22 LR 3.8in Tan
.22 LRTaurus TX22 Gen 2 .22 LR 4.60in Black
.22 LRTaurus TX22 Gen 2 T.O.R.O. .22 LR 4.6in Black/ODG
.22 LRTaurus TX22 Gen 2 TORO .22 LR FDE/Black
.22 LRRuger Mark IV .22 LR 4.4in Black
.22 LRCMMG Banshee Mk4 .22 LR 9in Armor Black
.22 LRHammerli Arms Forge H1 Trump 2024 .22 LR 5in Black
.22 LRBeretta 21A Bobcat Kale Slushy .22 LR 2.9in OD Green
.22 LRBlue Line Mauser M20 .22 LR 4.7in Robins Egg Blue/Black
.22 LRMauser 1911 .22 LR 5in Black
.22 LRKel-Tec P17 .22 LR 3.80in Blue/Black
.22 LRVolquartsen Mini Mamba .22 LR 3in Black
.22 LRCMMG MK4 DL-44 Blaster .22 LR 5in Battle Worn Armor Black
.22 LRRetay RXP .22 LR 4in FDE
.22 LRTaurus TX22 Gen 2 .22 LR
.22 LRRuger Mark IV 22/45 Collector's Series .22 LR 5.5in Blued
.22 LRRuger Mark IV 22/45 .22 LR 3in Black
.22 LRRuger Mark IV 22/45 Tactical .22 LR 3in ODG
.22 LRRuger Mark IV 22/45 Lite .22LR 4.4in Blue/Black
.22 LRRuger Mark IV Lite .22 LR 4.4in Black
.22 LRKel-Tec P17 .22 LR 3.8in OD Green
.22 LRSig Sauer P322 .22 LR 4in Black
.22 LRKel-Tec P17 .22 LR 3.80in Tan/Black
.22 LRBeretta 20X Bobcat .22 LR 2.8in Black
.22 LRArmalite ISSC M22 .22 LR Compact Semi-Auto Pistol
.22 LRRuger Mark IV 22/45 .22 LR 4.4in Black
.22 LRRetay RXP22 .22 LR 4in OD Green Black Threaded Barrel
.22 LRRetay RXP22 .22 LR 4in Black/Grey
.22 LRRuger Mark IV 22/45 250th Anniversary .22 LR 4.4in Stainless
.22 LRRuger Mark IV 22/45 Tactical .22 LR 4.4in Two-Tone
.22 LRRuger Mark IV 22/45 Lite .22 LR 4.4in Champagne
.22 LRRetay RXP22 .22 LR 4in Black
.22 LRBrowning Buck Mark .22 LR 5.5in Black
.22 LRRetay RXP22 .22 LR 4in FDE Threaded Barrel
.22 LRBrowning Buck Mark Plus URX .22 LR 5.9in Gray
.22 LRRuger Mark IV Lite .22 LR 4.4in Blue
.22 LRRetay USA RXP .22 LR 4in Black
.22 LRTaurus TX22 Gen 2 T.O.R.O. .22 LR Black
.22 LRTaurus 22 TUC .22 LR 2.5in Stainless Blue
.22 LRTaurus TX22 .22 LR Black
.22 LRBlue Line Solutions Mauser TacOps PK .22 LR 5in Black
.22 LRRetay RXP .22 LR 4in OD Green
.22 LRRetay RXP22 .22 LR 4in OD Green Threaded Barrel
.22 LRRetay RXP .22 LR 4in OD Green
.22 LRRetay RXP .22 LR 4in OD Green & Black
Showing 1-48 of 108 firearms tagged with .22 LR Semi-Automatic Handguns
Related Tags
About .22 LR Semi-Automatic Handguns
Discover the best firearms tagged with ".22 LR Semi-Automatic Handguns" at GunsNation. Browse our collection to find the perfect firearm for your needs.