.22 LR Semi-Automatic Handguns - Guns For Sale
Explore .22 LR semi-automatic handguns built for rimfire range time, target practice, plinking, and low-recoil training. This selection includes compact pistols like the Armalite ISSC M22 and Beretta 21A Bobcat, plus full-size target and 1911-style options such as the Ruger 22/45, Ruger Mark III, Mauser 1911, and Chiappa 1911-22.
Browse models with practical barrel lengths, familiar controls, black, stainless, OD green, and FDE finishes, and range-ready configurations like the FN 502 Tactical and Standard Manufacturing Jackhammer. These .22 LR semi-auto pistols fit shoppers looking for a lighter-shooting handgun for practice sessions, skill building, or classic rimfire fun.
GunsNation lists 125 .22 LR Semi-Automatic Handguns listings from multiple verified dealers. Compare them side by side to find the best price.
Frequently asked questions
- How many .22 LR Semi-Automatic Handguns listings are on GunsNation?
- GunsNation currently aggregates 125 .22 LR Semi-Automatic Handguns listings from verified dealers, so you can compare prices in one place.
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.22 LRMauser M20 .22 LR 4.7in Rose Gold
.22 LRBLG Mauser HSr .22 LR 3.5in Frozen Grey
.22 LRHammerli Forge H1 .22 LR 5in Black
.22 LRFN 502 Tactical .22 LR 4.60in Black
.22 LRFN 502 Tactical .22 LR 4.60in FDE
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.22 LRStandard Manufacturing Jackhammer .22 LR 5.75in
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.22 LRTaurus TX22 .22LR 4.60in Blue/Black
.22 LRTaurus TX22 Gen 2 .22 LR 4.6in Black
.22 LRTaurus TX22 Gen 2 TORO .22 LR FDE/Black
.22 LRTaurus TX22 Gen 2 .22 LR 4.60in Black
.22 LRRuger Mark IV 22/45 .22 LR 4.4in Gray
.22 LRKel-Tec CP33 .22 LR 5.5in Threaded MultiCam Black Slide
.22 LRTaurus TX22 Gen 2 .22 LR 4.6in FDE/Black 10rd Threaded
.22 LRTaurus TX22 Gen 2 T.O.R.O. .22 LR 4.6in Black/ODG
.22 LRChiappa 1911-22 Custom .22 LR 5in Black
.22 LRKel-Tec P17 .22 LR 3.8in Tan
.22 LRRuger Mark IV Lite .22 LR 4.4in Black
.22 LRTaurus TX22 Gen 2 .22 LR 4.6in FDE/Black Threaded
.22 LRRuger Mark IV .22 LR 4.4in Black
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.22 LRTaurus TX22 .22 LR 4.6in OD Green
.22 LRKel-Tec P17 .22 LR 3.8in Green/Black
.22 LRTaurus TX22 Gen 2 T.O.R.O. .22 LR 4.6in Cyan/Black
.22 LRTaurus TX22 Gen 2 TORO .22 LR 4.1in Black
.22 LRBrowning Buck Mark .22 LR 5.5in Black
.22 LRBLG Mauser HSr .22 LR 3.5in Black Wood Grips
.22 LRCMMG Banshee Mk4 .22 LR 9in Armor Black
.22 LRHammerli Arms Forge H1 Trump 2024 .22 LR 5in Black
.22 LRRuger Mark III .22 LR 5.5in Stainless
.22 LRTaurus TX22 .22 LR 4.6in Black
.22 LRVolquartsen Mini Mamba .22 LR 3in Black
.22 LRRuger Mark IV 22/45 Lite .22LR 4.4in Blue/Black
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.22 LRRuger Mark IV Lite .22 LR 4.4in Blue
.22 LRKel-Tec P17 .22 LR 3.8in OD Green
.22 LRKel-Tec P17 .22 LR 3.80in Tan/Black
.22 LRRuger Mark IV 22/45 Tactical .22 LR 4.4in Two-Tone
.22 LRTaurus TX22 Gen 2 T.O.R.O. .22 LR Black
.22 LRCMMG MK4 DL-44 Blaster .22 LR 5in Battle Worn Armor Black
.22 LRTaurus TX22 Gen 2 .22 LR
.22 LRBeretta 21A Bobcat Kale Slushy .22 LR 2.9in OD Green
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.22 LRTaurus TX22 .22 LR Black
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.22 LRRuger Mark IV 22/45 .22 LR 3in Black
.22 LRArmalite ISSC M22 Gen 1 .22 LR Compact Semi-Auto Pistol
.22 LRKel-Tec P17 .22 LR 3.80in Blue/Black
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.22 LRRuger Mark IV 22/45 250th Anniversary .22 LR 4.4in Stainless
.22 LRRuger Mark IV 22/45 Lite .22 LR 4.4in Black
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.22 LRRuger Mark IV 22/45 Tactical .22 LR 3in ODG
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.22 LRTaurus TX-22 .22 LR 4.1in Cyan
.22 LRRetay RXP .22 LR 4in FDE
Showing 1-48 of 125 firearms tagged with .22 LR Semi-Automatic Handguns
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About .22 LR Semi-Automatic Handguns
Discover the best firearms tagged with ".22 LR Semi-Automatic Handguns" at GunsNation. Browse our collection to find the perfect firearm for your needs.